rny protein (Wolinella succinogenes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

rny

KH DOMAIN PROTEIN; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family. (472 aa)

Predicted Functional Partners:

WS0072

0.672

WS0073

0.578

FLIL

0.562

RADA

0.544

FTSY

0.540

PNP

0.506

rnj

0.476

ftsI

0.468

WS1482

0.458

WS0757

0.431

Your Current Organism:

Wolinella succinogenes

NCBI taxonomy Id: 273121
Other names: W. succinogenes DSM 1740, Wolinella succinogenes DSM 1740

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FLIL	rny	WS1970	WS0071	HYPOTHETICAL PROTEIN-Flagellar basal body associated protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.	KH DOMAIN PROTEIN; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.	0.562
FTSY	RADA	WS0074	WS0075	SIGNAL RECOGNITION PARTICLE PROTEIN; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.	DNA REPAIR PROTEIN RADA HOMOLOG DNA REPAIR PROTEIN SMS HOMOLOG; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.	0.816
FTSY	WS0072	WS0074	WS0072	SIGNAL RECOGNITION PARTICLE PROTEIN; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.	Conserved hypothetical protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	0.635
FTSY	WS0073	WS0074	WS0073	SIGNAL RECOGNITION PARTICLE PROTEIN; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.	PUTATIVE LIPOPROTEIN THIREDOXIN.	0.814
FTSY	rny	WS0074	WS0071	SIGNAL RECOGNITION PARTICLE PROTEIN; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.	KH DOMAIN PROTEIN; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.	0.540
PNP	WS1482	WS0899	WS1482	NUCLEOTIDYLTRANSFERASE; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.	ATP-DEPENDENT RNA HELICASE, DEAD-BOX FAMILY DEAD.	0.965
PNP	rnj	WS0899	WS0066	NUCLEOTIDYLTRANSFERASE; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.	Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.	0.420
PNP	rny	WS0899	WS0071	NUCLEOTIDYLTRANSFERASE; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.	KH DOMAIN PROTEIN; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.	0.506
RADA	FTSY	WS0075	WS0074	DNA REPAIR PROTEIN RADA HOMOLOG DNA REPAIR PROTEIN SMS HOMOLOG; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.	SIGNAL RECOGNITION PARTICLE PROTEIN; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.	0.816
RADA	WS0072	WS0075	WS0072	DNA REPAIR PROTEIN RADA HOMOLOG DNA REPAIR PROTEIN SMS HOMOLOG; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.	Conserved hypothetical protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	0.633
RADA	WS0073	WS0075	WS0073	DNA REPAIR PROTEIN RADA HOMOLOG DNA REPAIR PROTEIN SMS HOMOLOG; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.	PUTATIVE LIPOPROTEIN THIREDOXIN.	0.790
RADA	rny	WS0075	WS0071	DNA REPAIR PROTEIN RADA HOMOLOG DNA REPAIR PROTEIN SMS HOMOLOG; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.	KH DOMAIN PROTEIN; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.	0.544
WS0072	FTSY	WS0072	WS0074	Conserved hypothetical protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	SIGNAL RECOGNITION PARTICLE PROTEIN; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.	0.635
WS0072	RADA	WS0072	WS0075	Conserved hypothetical protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	DNA REPAIR PROTEIN RADA HOMOLOG DNA REPAIR PROTEIN SMS HOMOLOG; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.	0.633
WS0072	WS0073	WS0072	WS0073	Conserved hypothetical protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	PUTATIVE LIPOPROTEIN THIREDOXIN.	0.584
WS0072	rny	WS0072	WS0071	Conserved hypothetical protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	KH DOMAIN PROTEIN; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.	0.672
WS0073	FTSY	WS0073	WS0074	PUTATIVE LIPOPROTEIN THIREDOXIN.	SIGNAL RECOGNITION PARTICLE PROTEIN; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.	0.814
WS0073	RADA	WS0073	WS0075	PUTATIVE LIPOPROTEIN THIREDOXIN.	DNA REPAIR PROTEIN RADA HOMOLOG DNA REPAIR PROTEIN SMS HOMOLOG; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.	0.790
WS0073	WS0072	WS0073	WS0072	PUTATIVE LIPOPROTEIN THIREDOXIN.	Conserved hypothetical protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	0.584
WS0073	rny	WS0073	WS0071	PUTATIVE LIPOPROTEIN THIREDOXIN.	KH DOMAIN PROTEIN; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.	0.578