STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRDAFUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT; The fumarate reductase enzyme complex is required for fumarate respiration using formate or sulfide as electron donor. Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (656 aa)    
Predicted Functional Partners:
FRDC2
FRDC2 PROTEIN.
 
 0.999
FRDB
FUMARATE REDUCTASE IRON-SULFUR PROTEIN; The fumarate reductase enzyme complex is required for fumarate respiration using formate or sulfide as electron donor. Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 0.999
FRDC
FUMARATE REDUCTASE CYTOCHROME B SUBUNIT; The fumarate reductase enzyme complex is required for fumarate respiration using formate or sulfide as electron donor.
 
 0.999
SDHB
SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN; Iron-sulfur subunit of 8-methylmenaquinol:fumarate reductase (MFR), that catalyzes the reduction of fumarate using 8- methylmenaquinol-6 as electron donor. The complex shows no succinate oxidation activity. Is involved in anaerobic metabolism. Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 0.997
sdhC
SUCCINATE DEHYDROGENASE SUBUNIT C; Membrane anchor subunit of 8-methylmenaquinol:fumarate reductase (MFR), that catalyzes the reduction of fumarate using 8- methylmenaquinol-6 as electron donor. The complex shows no succinate oxidation activity. Is involved in anaerobic metabolism. SdhE likely contains the quinol/quinone binding site.
 
 
 0.978
SUCC
SUCCINYL-COA SYNTHETASE BETA CHAIN; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.963
SUCD
SUCCINYL-COA SYNTHETASE ALPHA CHAIN; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.963
FUMB
FUMARATE HYDRATASE B, ALPHA SUBUNIT.
  
 
 0.938
FUMB-2
FUMARATE HYDRATASE B, BETA SUBUNIT.
  
 
 0.938
FRDA-2
FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT.
  
 
 
0.922
Your Current Organism:
Wolinella succinogenes
NCBI taxonomy Id: 273121
Other names: W. succinogenes DSM 1740, Wolinella succinogenes DSM 1740
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