STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpB2TRYPTOPHAN SYNTHASE BETA CHAIN; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (402 aa)    
Predicted Functional Partners:
TRPA
TRYPTOPHAN SYNTHASE ALPHA CHAIN; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 0.999
TRPC
INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE; Belongs to the TrpC family.
 
 0.999
TRPF
PUTATIVE N-5'-PHOSPHORIBOSYLANTHRANILATE ISOMERASE; Belongs to the TrpF family.
  
 0.979
trpD
ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
  
 0.940
ILVA
THREONINE DEHYDRATASE BIOSYNTHETIC.
  
 0.926
SERB
PUTATIVE PHOSPHOSERINE PHOSPHATASE.
   
 
 0.916
GLYA3
SERINE HYDROXYMETHYLTRANSFERASE (SERINE METHYLASE)(GLYCINE HYDROXYMETHYLTRANSFERASE) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.910
trpB
PUTATIVE TRYPTOPHAN SYNTHASE; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
  
 
0.905
PSSA
PHOSPHATIDYLTRANSFERASE; CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
  0.900
WS2172
ANTHRANILATE SYNTHASE COMPONENT II.
 
  
 0.820
Your Current Organism:
Wolinella succinogenes
NCBI taxonomy Id: 273121
Other names: W. succinogenes DSM 1740, Wolinella succinogenes DSM 1740
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