STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PURAADENYLOSUCCINATE SYNTHETASE IMP-ASPARTATE LIGASEADSS AMPSASE; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (415 aa)    
Predicted Functional Partners:
PURB
ADENYLOSUCCINATE LYASE; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 0.996
GUAB
INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.988
PURH
PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE / IMPCYCLOHYDROLASE.
  
 0.980
PYRB
ASPARTATE CARBAMOYLTRANSFERASE; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
 
 0.938
ARGG
ARGININOSUCCINATE SYNTHASE CITRULLINE--ASPARTATELIGASE; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.938
SURE
SURVIVAL PROTEIN SURE-Predicted acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.915
ASPB
ASPARTATE AMINOTRANSFERASE.
   
 0.914
WS1604
ASPARTATE OXIDASE; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
 0.912
WBPS
WBPS.
   
 
 0.910
glmS
Glutamine amidotransferase type-2 domain-containing protein; GALACTOSYL TRANSFERASE, GDP-MANNOSE PYROPHOSPHORYLASE,PHOSPHOMANNOMUTASE, UDP-GALACTOSE 4-EPIMERASE, GALACTOSYL TRANSFERASE,NUCLEOTIDE SUGAR DEHYDROGENASE, NUCLEOTIDE SUGAR EPIMERASE, ANDPUTATIVE EPIMERASE/DEHYDRATASE GENES; AND UNKNOWN GENES.
   
 
 0.910
Your Current Organism:
Wolinella succinogenes
NCBI taxonomy Id: 273121
Other names: W. succinogenes DSM 1740, Wolinella succinogenes DSM 1740
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