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LIS1 protein (Verticillium dahliae) - STRING interaction network
"LIS1" - Nuclear distribution protein PAC1 in Verticillium dahliae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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LIS1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein- mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family (463 aa)    
Predicted Functional Partners:
VDAG_00518
Dynein heavy chain (4367 aa)
       
 
  0.954
VDAG_07008
Dynactin (1337 aa)
       
 
  0.952
VDAG_06760
Patatin-like phospholipase domain-containing protein; Lipid hydrolase (766 aa)
         
    0.900
VDAG_00734
Lysophospholipase; Cytosolic phospholipase A2 zeta (814 aa)
         
    0.900
VDAG_03673
Nuclear distribution protein nudE (601 aa)
       
 
  0.874
VDAG_04301
Uncharacterized protein (867 aa)
       
 
  0.867
VDAG_01071
Phospholipase A2 (644 aa)
       
  0.859
VDAG_01000
Dynein light chain (100 aa)
       
 
  0.840
VDAG_04511
Uncharacterized protein (434 aa)
     
 
  0.827
VDAG_06843
Nuclear movement protein nudC (191 aa)
       
 
  0.823
Your Current Organism:
Verticillium dahliae
NCBI taxonomy Id: 27337
Other names: CBS 130341, NRRL 54785, PD322, UC 1953893, V. dahliae, Verticillium dahliae
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