STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (198 aa)    
Predicted Functional Partners:
pyrF
Orotidine 5-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.999
pyrD
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate.
  
 0.990
pyrB
Aspartate carbamoyltransferase catalytic subunit; Catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.980
EH55_09450
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.980
pyrR
Bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
  
 
 0.976
EH55_12145
Dihydroorotate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.975
EH55_07795
Dihydroorotase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.962
EH55_04750
Carbamoyl-phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.957
carA
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family.
  
  
 0.950
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.930
Your Current Organism:
Synergistes jonesii
NCBI taxonomy Id: 2754
Other names: ATCC 49833, S. jonesii, strain 78-1
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