node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | R7Q9P7_CHOCR | R7QKB7 | R7Q9P7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA mismatch repair protein MLH1. | 0.733 |
FEN1 | R7Q9S7_CHOCR | R7QKB7 | R7Q9S7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.801 |
FEN1 | R7QAT8_CHOCR | R7QKB7 | R7QAT8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA repair protein complementing XPG, RAD2. | 0.481 |
FEN1 | R7QAX9_CHOCR | R7QKB7 | R7QAX9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.639 |
FEN1 | R7QC97_CHOCR | R7QKB7 | R7QC97 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.998 |
FEN1 | R7QGD9_CHOCR | R7QKB7 | R7QGD9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA mismatch repair protein MutL. | 0.662 |
FEN1 | R7QMJ8_CHOCR | R7QKB7 | R7QMJ8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | MUTSd domain-containing protein. | 0.521 |
FEN1 | R7QNF4_CHOCR | R7QKB7 | R7QNF4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA_MISMATCH_REPAIR_2 domain-containing protein. | 0.521 |
FEN1 | R7QNH0_CHOCR | R7QKB7 | R7QNH0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.639 |
FEN1 | R7QSP3_CHOCR | R7QKB7 | R7QSP3 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA mismatch repair protein MutS homolog, MSH4. | 0.560 |
R7Q9P7_CHOCR | FEN1 | R7Q9P7 | R7QKB7 | DNA mismatch repair protein MLH1. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.733 |
R7Q9P7_CHOCR | R7Q9S7_CHOCR | R7Q9P7 | R7Q9S7 | DNA mismatch repair protein MLH1. | Uncharacterized protein. | 0.986 |
R7Q9P7_CHOCR | R7QAT8_CHOCR | R7Q9P7 | R7QAT8 | DNA mismatch repair protein MLH1. | DNA repair protein complementing XPG, RAD2. | 0.719 |
R7Q9P7_CHOCR | R7QAX9_CHOCR | R7Q9P7 | R7QAX9 | DNA mismatch repair protein MLH1. | Uncharacterized protein. | 0.983 |
R7Q9P7_CHOCR | R7QC97_CHOCR | R7Q9P7 | R7QC97 | DNA mismatch repair protein MLH1. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.900 |
R7Q9P7_CHOCR | R7QGD9_CHOCR | R7Q9P7 | R7QGD9 | DNA mismatch repair protein MLH1. | DNA mismatch repair protein MutL. | 0.987 |
R7Q9P7_CHOCR | R7QMJ8_CHOCR | R7Q9P7 | R7QMJ8 | DNA mismatch repair protein MLH1. | MUTSd domain-containing protein. | 0.809 |
R7Q9P7_CHOCR | R7QNF4_CHOCR | R7Q9P7 | R7QNF4 | DNA mismatch repair protein MLH1. | DNA_MISMATCH_REPAIR_2 domain-containing protein. | 0.880 |
R7Q9P7_CHOCR | R7QNH0_CHOCR | R7Q9P7 | R7QNH0 | DNA mismatch repair protein MLH1. | Uncharacterized protein. | 0.978 |
R7Q9P7_CHOCR | R7QSP3_CHOCR | R7Q9P7 | R7QSP3 | DNA mismatch repair protein MLH1. | DNA mismatch repair protein MutS homolog, MSH4. | 0.903 |