node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PEPE_0228 | PEPE_0559 | PEPE_0228 | PEPE_0559 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.905 |
PEPE_0228 | PEPE_0561 | PEPE_0228 | PEPE_0561 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Putative transcription activator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.981 |
PEPE_0228 | PEPE_1820 | PEPE_0228 | PEPE_1820 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.437 |
PEPE_0228 | thiE | PEPE_0228 | PEPE_0560 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.998 |
PEPE_0228 | thiM | PEPE_0228 | PEPE_0558 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.916 |
PEPE_0557 | thiM | PEPE_0557 | PEPE_0558 | Hypothetical protein; Belongs to the UPF0337 (CsbD) family. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.410 |
PEPE_0559 | PEPE_0228 | PEPE_0559 | PEPE_0228 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.905 |
PEPE_0559 | PEPE_0561 | PEPE_0559 | PEPE_0561 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Putative transcription activator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.995 |
PEPE_0559 | PEPE_0562 | PEPE_0559 | PEPE_0562 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | ATP-dependent DNA helicase, RecQ-like protein. | 0.514 |
PEPE_0559 | PEPE_1820 | PEPE_0559 | PEPE_1820 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.437 |
PEPE_0559 | thiE | PEPE_0559 | PEPE_0560 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.999 |
PEPE_0559 | thiM | PEPE_0559 | PEPE_0558 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.987 |
PEPE_0561 | PEPE_0228 | PEPE_0561 | PEPE_0228 | Putative transcription activator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.981 |
PEPE_0561 | PEPE_0559 | PEPE_0561 | PEPE_0559 | Putative transcription activator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.995 |
PEPE_0561 | PEPE_0562 | PEPE_0561 | PEPE_0562 | Putative transcription activator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | ATP-dependent DNA helicase, RecQ-like protein. | 0.503 |
PEPE_0561 | thiE | PEPE_0561 | PEPE_0560 | Putative transcription activator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.959 |
PEPE_0561 | thiM | PEPE_0561 | PEPE_0558 | Putative transcription activator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.994 |
PEPE_0562 | PEPE_0559 | PEPE_0562 | PEPE_0559 | ATP-dependent DNA helicase, RecQ-like protein. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.514 |
PEPE_0562 | PEPE_0561 | PEPE_0562 | PEPE_0561 | ATP-dependent DNA helicase, RecQ-like protein. | Putative transcription activator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.503 |
PEPE_0562 | thiE | PEPE_0562 | PEPE_0560 | ATP-dependent DNA helicase, RecQ-like protein. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.493 |