node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PEPE_0693 | PEPE_0872 | PEPE_0693 | PEPE_0872 | Replicative DNA helicase loader DnaI. | Hypothetical protein. | 0.427 |
PEPE_0693 | PEPE_1205 | PEPE_0693 | PEPE_1205 | Replicative DNA helicase loader DnaI. | Competence protein. | 0.439 |
PEPE_0693 | PEPE_1260 | PEPE_0693 | PEPE_1260 | Replicative DNA helicase loader DnaI. | Hypothetical protein; Belongs to the UPF0473 family. | 0.668 |
PEPE_0693 | ezrA | PEPE_0693 | PEPE_1295 | Replicative DNA helicase loader DnaI. | Negative regulator of septation ring formation; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | 0.570 |
PEPE_0693 | recU | PEPE_0693 | PEPE_0932 | Replicative DNA helicase loader DnaI. | Penicillin-binding protein-related factor A, putative recombinase; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. | 0.559 |
PEPE_0872 | PEPE_0693 | PEPE_0872 | PEPE_0693 | Hypothetical protein. | Replicative DNA helicase loader DnaI. | 0.427 |
PEPE_0872 | PEPE_1205 | PEPE_0872 | PEPE_1205 | Hypothetical protein. | Competence protein. | 0.587 |
PEPE_0872 | PEPE_1260 | PEPE_0872 | PEPE_1260 | Hypothetical protein. | Hypothetical protein; Belongs to the UPF0473 family. | 0.634 |
PEPE_0872 | ezrA | PEPE_0872 | PEPE_1295 | Hypothetical protein. | Negative regulator of septation ring formation; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | 0.636 |
PEPE_0872 | gpsB | PEPE_0872 | PEPE_0934 | Hypothetical protein. | Cell division initiation protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | 0.489 |
PEPE_0872 | recU | PEPE_0872 | PEPE_0932 | Hypothetical protein. | Penicillin-binding protein-related factor A, putative recombinase; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. | 0.739 |
PEPE_0872 | spxA | PEPE_0872 | PEPE_1207 | Hypothetical protein. | Arsenate reductase related protein, glutaredoxin family; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | 0.654 |
PEPE_0931 | PEPE_0933 | PEPE_0931 | PEPE_0933 | Membrane carboxypeptidase (penicillin-binding protein). | Hypothetical protein; Belongs to the UPF0398 family. | 0.612 |
PEPE_0931 | ezrA | PEPE_0931 | PEPE_1295 | Membrane carboxypeptidase (penicillin-binding protein). | Negative regulator of septation ring formation; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | 0.445 |
PEPE_0931 | gpsB | PEPE_0931 | PEPE_0934 | Membrane carboxypeptidase (penicillin-binding protein). | Cell division initiation protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | 0.887 |
PEPE_0931 | recU | PEPE_0931 | PEPE_0932 | Membrane carboxypeptidase (penicillin-binding protein). | Penicillin-binding protein-related factor A, putative recombinase; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. | 0.837 |
PEPE_0933 | PEPE_0931 | PEPE_0933 | PEPE_0931 | Hypothetical protein; Belongs to the UPF0398 family. | Membrane carboxypeptidase (penicillin-binding protein). | 0.612 |
PEPE_0933 | gpsB | PEPE_0933 | PEPE_0934 | Hypothetical protein; Belongs to the UPF0398 family. | Cell division initiation protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | 0.704 |
PEPE_0933 | recU | PEPE_0933 | PEPE_0932 | Hypothetical protein; Belongs to the UPF0398 family. | Penicillin-binding protein-related factor A, putative recombinase; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. | 0.729 |
PEPE_1130 | recU | PEPE_1130 | PEPE_0932 | Exonuclease RecJ. | Penicillin-binding protein-related factor A, putative recombinase; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. | 0.582 |