STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS11741L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (348 aa)    
Predicted Functional Partners:
NBR_LOCUS12757
Citrate synthase; Belongs to the citrate synthase family.
  
 0.981
NBR_LOCUS11147
Malate synthase; Belongs to the malate synthase family.
  
 0.976
NBR_LOCUS18695
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.962
NBR_LOCUS8589
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.961
NBR_LOCUS12326
Aspartate aminotransferase.
   
 0.938
NBR_LOCUS9619
Probable fumarate hydratase, mitochondrial (inferred by orthology to a C. elegans protein).
  
 0.934
NBR_LOCUS7871
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.934
NBR_LOCUS2
Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.914
NBR_LOCUS11706
Probable D-lactate dehydrogenase, mitochondrial (inferred by orthology to a human protein).
   
 
 0.912
NBR_LOCUS13810
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
  
 0.910
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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