STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rsbWSwitch protein/serine kinase and anti-sigma factor (inhibitory sigma-B binding protein); Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). (161 aa)    
Predicted Functional Partners:
sigB
RNA polymerase sigma-37 factor (sigma-B); Belongs to the sigma-70 factor family.
 
 
 0.997
rsbU
Serine phosphatase.
 
 0.987
rsbS
Antagonist of RsbT.
 
 0.983
rsbX
Serine phosphatase.
 
 0.983
rsbV
Anti-anti-sigma factor (antagonist of RsbW); Belongs to the anti-sigma-factor antagonist family.
 
 
 0.982
rsbR
RbsR.
 
 0.981
sigF
RNA polymerase sporulation-specific sigma factor (sigma-F); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.912
yqhA
Putative sulphate transporter YqhA.
 
 0.911
spoIIAA
Anti-anti-sigma factor (antagonist of SpoIIAB); Belongs to the anti-sigma-factor antagonist family.
 
 
 0.895
rsbT
Switch protein/serine-threonine kinase.
 
   
 0.878
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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