node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BL00947 | hemH | BL00947 | BL01073 | Pectate lyase, Polysaccharide Lyase Family 1; Cleaves unsaturated oligo-galacturonides from pectin. The major product is trigalacturonate; digalacturonate and tetragalacturonate are also produced. Activity on methylated pectins decreases with an increasing degree of methylation (By similarity). Belongs to the polysaccharide lyase 1 family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.529 |
BL00947 | lanA | BL00947 | BL05375 | Pectate lyase, Polysaccharide Lyase Family 1; Cleaves unsaturated oligo-galacturonides from pectin. The major product is trigalacturonate; digalacturonate and tetragalacturonate are also produced. Activity on methylated pectins decreases with an increasing degree of methylation (By similarity). Belongs to the polysaccharide lyase 1 family. | Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...] | 0.525 |
BL00947 | lanM2 | BL00947 | BL00948 | Pectate lyase, Polysaccharide Lyase Family 1; Cleaves unsaturated oligo-galacturonides from pectin. The major product is trigalacturonate; digalacturonate and tetragalacturonate are also produced. Activity on methylated pectins decreases with an increasing degree of methylation (By similarity). Belongs to the polysaccharide lyase 1 family. | Lantibiotic modifying enzyme. | 0.408 |
cinA | lanA | BL05163 | BL05375 | Competence-damage inducible protein; Belongs to the CinA family. | Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...] | 0.472 |
hemH | BL00947 | BL01073 | BL00947 | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | Pectate lyase, Polysaccharide Lyase Family 1; Cleaves unsaturated oligo-galacturonides from pectin. The major product is trigalacturonate; digalacturonate and tetragalacturonate are also produced. Activity on methylated pectins decreases with an increasing degree of methylation (By similarity). Belongs to the polysaccharide lyase 1 family. | 0.529 |
hemH | lanA | BL01073 | BL05375 | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...] | 0.479 |
hemH | licT | BL01073 | BL02652 | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | Transcriptional antiterminator. | 0.518 |
lanA | BL00947 | BL05375 | BL00947 | Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...] | Pectate lyase, Polysaccharide Lyase Family 1; Cleaves unsaturated oligo-galacturonides from pectin. The major product is trigalacturonate; digalacturonate and tetragalacturonate are also produced. Activity on methylated pectins decreases with an increasing degree of methylation (By similarity). Belongs to the polysaccharide lyase 1 family. | 0.525 |
lanA | cinA | BL05375 | BL05163 | Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...] | Competence-damage inducible protein; Belongs to the CinA family. | 0.472 |
lanA | hemH | BL05375 | BL01073 | Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...] | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.479 |
lanA | lanG | BL05375 | BL00935 | Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...] | Lantibiotic immunity protein, MFS type transporter. | 0.432 |
lanA | lanM1 | BL05375 | BL00928 | Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...] | Lantibiotic modifying enzyme. | 0.470 |
lanA | lanM2 | BL05375 | BL00948 | Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...] | Lantibiotic modifying enzyme. | 0.772 |
lanA | lanP | BL05375 | BL00930 | Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...] | Intracellular serine protease; Belongs to the peptidase S8 family. | 0.613 |
lanA | lanR | BL05375 | BL00932 | Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...] | Transcriptional regulator. | 0.613 |
lanA | lanT | BL05375 | BL00929 | Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...] | Lantibiotic transport protein. | 0.545 |
lanA | licT | BL05375 | BL02652 | Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...] | Transcriptional antiterminator. | 0.613 |
lanG | lanA | BL00935 | BL05375 | Lantibiotic immunity protein, MFS type transporter. | Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...] | 0.432 |
lanG | lanM1 | BL00935 | BL00928 | Lantibiotic immunity protein, MFS type transporter. | Lantibiotic modifying enzyme. | 0.640 |
lanG | lanP | BL00935 | BL00930 | Lantibiotic immunity protein, MFS type transporter. | Intracellular serine protease; Belongs to the peptidase S8 family. | 0.756 |