STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lanALichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...] (74 aa)    
Predicted Functional Partners:
lanM2
Lantibiotic modifying enzyme.
     
 0.772
lanP
Intracellular serine protease; Belongs to the peptidase S8 family.
      
 0.613
lanR
Transcriptional regulator.
      
 0.613
licT
Transcriptional antiterminator.
      
 0.613
lanT
Lantibiotic transport protein.
      
 0.545
BL00947
Pectate lyase, Polysaccharide Lyase Family 1; Cleaves unsaturated oligo-galacturonides from pectin. The major product is trigalacturonate; digalacturonate and tetragalacturonate are also produced. Activity on methylated pectins decreases with an increasing degree of methylation (By similarity). Belongs to the polysaccharide lyase 1 family.
     
 0.525
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
      
 0.479
cinA
Competence-damage inducible protein; Belongs to the CinA family.
      
 0.472
lanM1
Lantibiotic modifying enzyme.
      
 0.470
lanG
Lantibiotic immunity protein, MFS type transporter.
      
 0.432
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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