node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Lxx10380 | Lxx10490 | Lxx10380 | Lxx10490 | Conserved hypothetical protein; Identified by sequence similarity. | Ribonuclease; Identified by sequence similarity. | 0.584 |
Lxx10380 | Lxx15490 | Lxx10380 | Lxx15490 | Conserved hypothetical protein; Identified by sequence similarity. | Conserved hypothetical protein; Identified by sequence similarity. | 0.766 |
Lxx10380 | glnE | Lxx10380 | Lxx10020 | Conserved hypothetical protein; Identified by sequence similarity. | Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...] | 0.674 |
Lxx10380 | rbpA | Lxx10380 | Lxx08360 | Conserved hypothetical protein; Identified by sequence similarity. | Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family. | 0.771 |
Lxx10490 | Lxx10380 | Lxx10490 | Lxx10380 | Ribonuclease; Identified by sequence similarity. | Conserved hypothetical protein; Identified by sequence similarity. | 0.584 |
Lxx10490 | glnE | Lxx10490 | Lxx10020 | Ribonuclease; Identified by sequence similarity. | Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...] | 0.665 |
Lxx14980 | glnA | Lxx14980 | Lxx10010 | Threonine synthase; Identified by sequence similarity. | Glutamine synthetase; Identified by sequence similarity; Belongs to the glutamine synthetase family. | 0.409 |
Lxx14980 | glnE | Lxx14980 | Lxx10020 | Threonine synthase; Identified by sequence similarity. | Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...] | 0.619 |
Lxx14980 | gltB | Lxx14980 | Lxx11320 | Threonine synthase; Identified by sequence similarity. | Glutamate synthase, alpha subunit; Identified by sequence similarity. | 0.598 |
Lxx15490 | Lxx10380 | Lxx15490 | Lxx10380 | Conserved hypothetical protein; Identified by sequence similarity. | Conserved hypothetical protein; Identified by sequence similarity. | 0.766 |
Lxx15490 | glnA | Lxx15490 | Lxx10010 | Conserved hypothetical protein; Identified by sequence similarity. | Glutamine synthetase; Identified by sequence similarity; Belongs to the glutamine synthetase family. | 0.424 |
Lxx15490 | glnA-2 | Lxx15490 | Lxx10080 | Conserved hypothetical protein; Identified by sequence similarity. | Glutamine synthetase; Identified by sequence similarity. | 0.424 |
Lxx15490 | glnE | Lxx15490 | Lxx10020 | Conserved hypothetical protein; Identified by sequence similarity. | Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...] | 0.533 |
Lxx15490 | rbpA | Lxx15490 | Lxx08360 | Conserved hypothetical protein; Identified by sequence similarity. | Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family. | 0.677 |
glnA | Lxx14980 | Lxx10010 | Lxx14980 | Glutamine synthetase; Identified by sequence similarity; Belongs to the glutamine synthetase family. | Threonine synthase; Identified by sequence similarity. | 0.409 |
glnA | Lxx15490 | Lxx10010 | Lxx15490 | Glutamine synthetase; Identified by sequence similarity; Belongs to the glutamine synthetase family. | Conserved hypothetical protein; Identified by sequence similarity. | 0.424 |
glnA | glnA-2 | Lxx10010 | Lxx10080 | Glutamine synthetase; Identified by sequence similarity; Belongs to the glutamine synthetase family. | Glutamine synthetase; Identified by sequence similarity. | 0.920 |
glnA | glnE | Lxx10010 | Lxx10020 | Glutamine synthetase; Identified by sequence similarity; Belongs to the glutamine synthetase family. | Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...] | 0.947 |
glnA | gltB | Lxx10010 | Lxx11320 | Glutamine synthetase; Identified by sequence similarity; Belongs to the glutamine synthetase family. | Glutamate synthase, alpha subunit; Identified by sequence similarity. | 0.988 |
glnA | panB | Lxx10010 | Lxx10000 | Glutamine synthetase; Identified by sequence similarity; Belongs to the glutamine synthetase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.688 |