node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
folB | folC | Lxx21470 | Lxx07980 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Folylpolyglutamate synthase; Identified by sequence similarity; Belongs to the folylpolyglutamate synthase family. | 0.812 |
folB | folE | Lxx21470 | Lxx21490 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I; Identified by sequence similarity. | 0.997 |
folB | folK | Lxx21470 | Lxx21460 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by sequence similarity. | 0.999 |
folB | folP | Lxx21470 | Lxx17980 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.994 |
folB | folP-2 | Lxx21470 | Lxx21480 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
folB | ftsH | Lxx21470 | Lxx21500 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.900 |
folB | ribA | Lxx21470 | Lxx04350 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.481 |
folC | folB | Lxx07980 | Lxx21470 | Folylpolyglutamate synthase; Identified by sequence similarity; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.812 |
folC | folE | Lxx07980 | Lxx21490 | Folylpolyglutamate synthase; Identified by sequence similarity; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase I; Identified by sequence similarity. | 0.812 |
folC | folK | Lxx07980 | Lxx21460 | Folylpolyglutamate synthase; Identified by sequence similarity; Belongs to the folylpolyglutamate synthase family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by sequence similarity. | 0.646 |
folC | folP | Lxx07980 | Lxx17980 | Folylpolyglutamate synthase; Identified by sequence similarity; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.996 |
folC | folP-2 | Lxx07980 | Lxx21480 | Folylpolyglutamate synthase; Identified by sequence similarity; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.996 |
folC | ndk | Lxx07980 | Lxx08000 | Folylpolyglutamate synthase; Identified by sequence similarity; Belongs to the folylpolyglutamate synthase family. | Nucleoside diphosphate kinase; Identified by sequence similarity. | 0.882 |
folC | ribA | Lxx07980 | Lxx04350 | Folylpolyglutamate synthase; Identified by sequence similarity; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.487 |
folE | folB | Lxx21490 | Lxx21470 | GTP cyclohydrolase I; Identified by sequence similarity. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.997 |
folE | folC | Lxx21490 | Lxx07980 | GTP cyclohydrolase I; Identified by sequence similarity. | Folylpolyglutamate synthase; Identified by sequence similarity; Belongs to the folylpolyglutamate synthase family. | 0.812 |
folE | folK | Lxx21490 | Lxx21460 | GTP cyclohydrolase I; Identified by sequence similarity. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by sequence similarity. | 0.998 |
folE | folP | Lxx21490 | Lxx17980 | GTP cyclohydrolase I; Identified by sequence similarity. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.873 |
folE | folP-2 | Lxx21490 | Lxx21480 | GTP cyclohydrolase I; Identified by sequence similarity. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.989 |
folE | ftsH | Lxx21490 | Lxx21500 | GTP cyclohydrolase I; Identified by sequence similarity. | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.992 |