STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2179 aa)    
Predicted Functional Partners:
CDC42
Uncharacterized protein.
   
 0.968
ARID4B
AT-rich interaction domain 4B.
      
 0.681
CORO1A
Coronin; Belongs to the WD repeat coronin family.
      
 0.656
RHOH
Ras homolog family member H.
   
 0.620
MAGT1
Magnesium transporter 1.
      
 0.593
RHOQ
Ras homolog family member Q.
   
 0.590
RHOJ
Ras homolog family member J.
   
 0.590
MST1R
Macrophage stimulating 1 receptor.
   
 
  0.570
MET
MET proto-oncogene, receptor tyrosine kinase.
   
 
  0.570
RAC3
Rac family small GTPase 3.
   
 0.561
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.