STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THRAThyroid hormone receptor alpha. (371 aa)    
Predicted Functional Partners:
RXRA
Retinoid X receptor alpha.
    
0.789
MED1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.679
ARNT
Aryl hydrocarbon receptor nuclear translocator.
    
 0.667
ncor1
Uncharacterized protein.
    
 0.654
NCOR2
Nuclear receptor corepressor 2.
    
 0.654
HIF1AN
Hypoxia inducible factor 1 subunit alpha inhibitor.
      
 0.610
SIK3
SIK family kinase 3.
    
 
 0.586
NR1D2
Nuclear receptor subfamily 1 group D member 2.
    
0.545
LOC100566411
Uncharacterized protein.
    
0.544
ATRN
Attractin.
      
 0.529
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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