STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1067 aa)    
Predicted Functional Partners:
CDC42
Uncharacterized protein.
   
 0.980
PIK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
  
  
0.979
Pik3r2
Uncharacterized protein.
    
 0.978
pik3r3
Uncharacterized protein.
    
 0.978
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.978
RAC1
Rac family small GTPase 1.
   
 0.966
IRS1
Insulin receptor substrate 1.
   
 0.965
IRS4
Insulin receptor substrate 4.
   
 0.965
LOC100567364
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
  
  
0.963
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
     
0.962
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.