node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DKK1 | LRP6 | ENSACAP00000005466 | ENSACAP00000004540 | Dickkopf WNT signaling pathway inhibitor 1. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.998 |
DKK1 | SOST | ENSACAP00000005466 | ENSACAP00000004670 | Dickkopf WNT signaling pathway inhibitor 1. | Sclerostin. | 0.633 |
DKK1 | WNT1 | ENSACAP00000005466 | ENSACAP00000008042 | Dickkopf WNT signaling pathway inhibitor 1. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.590 |
DKK1 | dkk2 | ENSACAP00000005466 | ENSACAP00000008158 | Dickkopf WNT signaling pathway inhibitor 1. | Dickkopf_N domain-containing protein. | 0.958 |
DKK1 | lrp5 | ENSACAP00000005466 | ENSACAP00000014430 | Dickkopf WNT signaling pathway inhibitor 1. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.994 |
FZD2 | FZD6 | ENSACAP00000012274 | ENSACAP00000009201 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.452 |
FZD2 | LRP6 | ENSACAP00000012274 | ENSACAP00000004540 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.949 |
FZD2 | WNT1 | ENSACAP00000012274 | ENSACAP00000008042 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.875 |
FZD2 | lrp5 | ENSACAP00000012274 | ENSACAP00000014430 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.949 |
FZD4 | FZD6 | ENSACAP00000002633 | ENSACAP00000009201 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.609 |
FZD4 | LRP6 | ENSACAP00000002633 | ENSACAP00000004540 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.982 |
FZD4 | WNT1 | ENSACAP00000002633 | ENSACAP00000008042 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.874 |
FZD4 | lrp5 | ENSACAP00000002633 | ENSACAP00000014430 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.981 |
FZD6 | FZD2 | ENSACAP00000009201 | ENSACAP00000012274 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.452 |
FZD6 | FZD4 | ENSACAP00000009201 | ENSACAP00000002633 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.609 |
FZD6 | FZD7 | ENSACAP00000009201 | ENSACAP00000005043 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.441 |
FZD6 | LOC100556214 | ENSACAP00000009201 | ENSACAP00000009583 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. | Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.476 |
FZD6 | LRP6 | ENSACAP00000009201 | ENSACAP00000004540 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.978 |
FZD6 | WNT1 | ENSACAP00000009201 | ENSACAP00000008042 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.910 |
FZD6 | lrp5 | ENSACAP00000009201 | ENSACAP00000014430 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.970 |