node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMD1 | DNMT3A | ENSACAP00000010972 | ENSACAP00000007951 | S-adenosylmethionine decarboxylase proenzyme. | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.900 |
AMD1 | LOC100558455 | ENSACAP00000010972 | ENSACAP00000016516 | S-adenosylmethionine decarboxylase proenzyme. | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | 0.434 |
AMD1 | MAT1A | ENSACAP00000010972 | ENSACAP00000004790 | S-adenosylmethionine decarboxylase proenzyme. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.955 |
AMD1 | MAT2B | ENSACAP00000010972 | ENSACAP00000021704 | S-adenosylmethionine decarboxylase proenzyme. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.908 |
AMD1 | MTR | ENSACAP00000010972 | ENSACAP00000003091 | S-adenosylmethionine decarboxylase proenzyme. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.434 |
AMD1 | TAT | ENSACAP00000010972 | ENSACAP00000007629 | S-adenosylmethionine decarboxylase proenzyme. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.750 |
DNMT3A | AMD1 | ENSACAP00000007951 | ENSACAP00000010972 | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine decarboxylase proenzyme. | 0.900 |
DNMT3A | MAT1A | ENSACAP00000007951 | ENSACAP00000004790 | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.911 |
DNMT3A | MAT2B | ENSACAP00000007951 | ENSACAP00000021704 | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.902 |
LOC100558455 | AMD1 | ENSACAP00000016516 | ENSACAP00000010972 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | S-adenosylmethionine decarboxylase proenzyme. | 0.434 |
LOC100558455 | LOC100563852 | ENSACAP00000016516 | ENSACAP00000015454 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Amine oxidase. | 0.904 |
LOC100558455 | LOC100566795 | ENSACAP00000016516 | ENSACAP00000011652 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Amino_oxidase domain-containing protein. | 0.904 |
LOC100558455 | LOC100566990 | ENSACAP00000016516 | ENSACAP00000022404 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Amine oxidase. | 0.901 |
LOC100558455 | LOC100567189 | ENSACAP00000016516 | ENSACAP00000023258 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Amine oxidase. | 0.904 |
LOC100558455 | MAT1A | ENSACAP00000016516 | ENSACAP00000004790 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.975 |
LOC100558455 | MAT2B | ENSACAP00000016516 | ENSACAP00000021704 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.944 |
LOC100558455 | MTR | ENSACAP00000016516 | ENSACAP00000003091 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.949 |
LOC100558455 | TAT | ENSACAP00000016516 | ENSACAP00000007629 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.935 |
LOC100563852 | LOC100558455 | ENSACAP00000015454 | ENSACAP00000016516 | Amine oxidase. | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | 0.904 |
LOC100563852 | LOC100566795 | ENSACAP00000015454 | ENSACAP00000011652 | Amine oxidase. | Amino_oxidase domain-containing protein. | 0.903 |