STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HAND2Heart and neural crest derivatives expressed 2. (228 aa)    
Predicted Functional Partners:
NKX2-5
NK2 homeobox 5.
   
 
 0.847
TBX20
T-box transcription factor 20.
   
  
 0.737
GATA4
GATA binding protein 4.
   
 0.695
EDN1
Endothelin 1.
      
 0.661
GLI3
GLI family zinc finger 3.
   
 
 0.622
TBX5
T-box transcription factor 5.
   
 0.610
HOXD12
Homeobox domain-containing protein.
    
 
 0.589
GATA3
GATA binding protein 3.
   
 0.583
HOXD13
Homeobox D13.
    
 
 0.581
TBX4
T-box transcription factor 4.
   
 0.579
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.