STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRUNE1Prune exopolyphosphatase 1. (450 aa)    
Predicted Functional Partners:
HDDC3
HD domain containing 3.
     
  0.900
APRT
Adenine phosphoribosyltransferase.
     
 0.839
GRB14
Growth factor receptor bound protein 14.
      
 0.704
TFAM
Transcription factor A, mitochondrial.
      
 0.688
gsk3a
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 
 0.676
CYFIP1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
      
 0.668
LOC100568155
CRAL-TRIO domain-containing protein.
 
    
 0.559
sdha
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
  
 0.546
IP6K1
Kinase; Belongs to the inositol phosphokinase (IPK) family.
      
 0.541
BNIP2
BCL2 interacting protein 2.
 
      0.537
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.