STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDGFRLPlatelet derived growth factor receptor like. (373 aa)    
Predicted Functional Partners:
PDGFB
Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.
   
 0.611
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
    
 0.598
GRB2
Growth factor receptor bound protein 2.
   
 0.597
NRP2
Neuropilin; Belongs to the neuropilin family.
     
 0.569
NRP1
Neuropilin; Belongs to the neuropilin family.
    
 0.559
PDGFRB
Platelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
0.541
RASA1
RAS p21 protein activator 1.
    
 0.521
GFRA3
GDNF family receptor alpha 3.
    
 0.501
GDNF
Glial cell derived neurotrophic factor.
    
 0.473
KITLG
Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.
    
 0.469
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.