STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GUK1Guanylate kinase 1. (197 aa)    
Predicted Functional Partners:
mrpl55
Uncharacterized protein.
   
  
 0.808
GMPS
Guanine monophosphate synthase.
  
 
 0.781
TFB1M
rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
 
  
 0.720
AK2
Adenylate kinase 2; Belongs to the adenylate kinase family.
   
 0.719
AK3
GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
   
 0.717
SPTLC1
Serine palmitoyltransferase long chain base subunit 1.
      
 0.706
SCARA5
Scavenger receptor class A member 5.
    
 0.687
APRT
Adenine phosphoribosyltransferase.
  
 
 0.663
BRD2
Bromodomain containing 2.
      
 0.636
MRPS12
Mitochondrial ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family.
  
  
 0.618
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.