STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTCHD1Patched domain containing 1. (905 aa)    
Predicted Functional Partners:
PLAGL2
PLAG1 like zinc finger 2.
      
 0.705
RIPK4
Receptor interacting serine/threonine kinase 4.
      
 0.695
SVEP1
Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1.
      
 0.668
PANX2
Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.
      
 0.656
SHANK3
SH3 and multiple ankyrin repeat domains 3.
      
 0.609
RAG2
Recombination activating 2.
      
 0.562
ZIC1
Zic family member 1.
      
 0.528
ENC1
Ectodermal-neural cortex 1.
      
 0.509
H9G8K7_ANOCA
PDZ domain-containing protein.
      
 0.479
DLGAP2
DLG associated protein 2.
   
  
 0.478
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.