node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATG12 | ATG16L1 | ENSACAP00000007908 | ENSACAP00000021861 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | Autophagy related 16 like 1. | 0.999 |
ATG12 | ATG3 | ENSACAP00000007908 | ENSACAP00000010099 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | Autophagy-related protein 3. | 0.999 |
ATG12 | ATG4A | ENSACAP00000007908 | ENSACAP00000011916 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | 0.568 |
ATG12 | ATG4B | ENSACAP00000007908 | ENSACAP00000000759 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | 0.608 |
ATG12 | ATG4C | ENSACAP00000007908 | ENSACAP00000007948 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | 0.547 |
ATG12 | ATG4D | ENSACAP00000007908 | ENSACAP00000015773 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | 0.547 |
ATG12 | ATG5 | ENSACAP00000007908 | ENSACAP00000005438 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | Autophagy protein 5; Involved in autophagic vesicle formation. | 0.999 |
ATG12 | ATG7 | ENSACAP00000007908 | ENSACAP00000010088 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | 0.999 |
ATG12 | GABARAPL2 | ENSACAP00000007908 | ENSACAP00000007380 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | GABA type A receptor associated protein like 2. | 0.989 |
ATG12 | NBR1 | ENSACAP00000007908 | ENSACAP00000013162 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | NBR1 autophagy cargo receptor. | 0.850 |
ATG16L1 | ATG12 | ENSACAP00000021861 | ENSACAP00000007908 | Autophagy related 16 like 1. | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | 0.999 |
ATG16L1 | ATG3 | ENSACAP00000021861 | ENSACAP00000010099 | Autophagy related 16 like 1. | Autophagy-related protein 3. | 0.997 |
ATG16L1 | ATG4A | ENSACAP00000021861 | ENSACAP00000011916 | Autophagy related 16 like 1. | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | 0.469 |
ATG16L1 | ATG4B | ENSACAP00000021861 | ENSACAP00000000759 | Autophagy related 16 like 1. | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | 0.540 |
ATG16L1 | ATG5 | ENSACAP00000021861 | ENSACAP00000005438 | Autophagy related 16 like 1. | Autophagy protein 5; Involved in autophagic vesicle formation. | 0.999 |
ATG16L1 | ATG7 | ENSACAP00000021861 | ENSACAP00000010088 | Autophagy related 16 like 1. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | 0.913 |
ATG16L1 | GABARAPL2 | ENSACAP00000021861 | ENSACAP00000007380 | Autophagy related 16 like 1. | GABA type A receptor associated protein like 2. | 0.979 |
ATG16L1 | NBR1 | ENSACAP00000021861 | ENSACAP00000013162 | Autophagy related 16 like 1. | NBR1 autophagy cargo receptor. | 0.720 |
ATG3 | ATG12 | ENSACAP00000010099 | ENSACAP00000007908 | Autophagy-related protein 3. | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | 0.999 |
ATG3 | ATG16L1 | ENSACAP00000010099 | ENSACAP00000021861 | Autophagy-related protein 3. | Autophagy related 16 like 1. | 0.997 |