STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRG1Neuregulin 1. (660 aa)    
Predicted Functional Partners:
ERBB4
Receptor protein-tyrosine kinase.
    
 0.834
ERBB2
Receptor protein-tyrosine kinase.
    
 0.833
ERBB3
Erb-b2 receptor tyrosine kinase 3.
    
 0.830
EGFR
Receptor protein-tyrosine kinase.
    
 0.722
EGF
Epidermal growth factor.
    
 0.706
SHC1
SHC adaptor protein 1.
     
 0.592
CSK
Tyrosine-protein kinase.
    
 0.582
rps27a
Ubiquitin-like domain-containing protein.
    
  0.575
RNF41
Ring finger protein 41.
    
 0.573
MEMO1
Mediator of cell motility 1.
   
  0.570
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.