STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHBDF2Rhomboid 5 homolog 2. (842 aa)    
Predicted Functional Partners:
METTL23
Methyltransferase like 23.
    
 
 0.714
PRPSAP1
Phosphoribosyl pyrophosphate synthetase associated protein 1.
      
 0.712
SPHK1
Sphingosine kinase 1.
      
 0.674
NPRL3
NPR3 like, GATOR1 complex subunit.
      
 0.611
DDX47
DEAD-box helicase 47; Belongs to the DEAD box helicase family.
  
  
 0.592
BPTF
Bromodomain PHD finger transcription factor.
      
 0.576
UBE2O
Ubiquitin conjugating enzyme E2 O.
 
 
  
 0.565
ADAM17
ADAM metallopeptidase domain 17.
    
 0.564
CYGB
Cytoglobin; Belongs to the globin family.
 
 
  
 0.561
Kank2
ANK_REP_REGION domain-containing protein.
      
 0.534
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.