STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JAK1Tyrosine-protein kinase. (1158 aa)    
Predicted Functional Partners:
IFNAR1
Interferon alpha and beta receptor subunit 1.
   
 0.994
STAT3
Signal transducer and activator of transcription.
   
 0.989
STAT2
Signal transducer and activator of transcription.
   
 0.986
SOCS3
Suppressor of cytokine signaling 3.
   
 0.980
STAT6
Signal transducer and activator of transcription.
   
 0.978
LOC100566752
Signal transducer and activator of transcription.
   
 0.978
LOC100560082
SH2 domain-containing protein.
   
 0.977
ifnar2
Uncharacterized protein.
   
 0.975
LOC103278369
Uncharacterized protein.
   
 0.973
JAK2
Tyrosine-protein kinase.
   
0.971
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.