VWA5B2 protein (Anolis carolinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

VWA5B2

Von Willebrand factor A domain containing 5B2. (1279 aa)

Predicted Functional Partners:

PARG

0.731

FEN1

0.608

clba1

0.579

FAAP24

0.565

TICRR

0.552

XRCC5

0.551

KIF9

0.546

XPC

0.530

LRATD2

0.529

HPF1

0.522

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAAP24	FEN1	ENSACAP00000007106	ENSACAP00000019151	FA core complex associated protein 24.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.582
FAAP24	VWA5B2	ENSACAP00000007106	ENSACAP00000008764	FA core complex associated protein 24.	Von Willebrand factor A domain containing 5B2.	0.565
FAAP24	XPC	ENSACAP00000007106	ENSACAP00000013318	FA core complex associated protein 24.	XPC complex subunit, DNA damage recognition and repair factor.	0.416
FAAP24	XRCC5	ENSACAP00000007106	ENSACAP00000009562	FA core complex associated protein 24.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.405
FAAP24	clba1	ENSACAP00000007106	ENSACAP00000018011	FA core complex associated protein 24.	Clathrin_bdg domain-containing protein.	0.454
FEN1	FAAP24	ENSACAP00000019151	ENSACAP00000007106	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	FA core complex associated protein 24.	0.582
FEN1	PARG	ENSACAP00000019151	ENSACAP00000020647	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Poly(ADP-ribose) glycohydrolase.	0.697
FEN1	VWA5B2	ENSACAP00000019151	ENSACAP00000008764	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Von Willebrand factor A domain containing 5B2.	0.608
FEN1	XPC	ENSACAP00000019151	ENSACAP00000013318	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	XPC complex subunit, DNA damage recognition and repair factor.	0.688
FEN1	XRCC5	ENSACAP00000019151	ENSACAP00000009562	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.730
HPF1	PARG	ENSACAP00000015377	ENSACAP00000020647	Histone PARylation factor 1.	Poly(ADP-ribose) glycohydrolase.	0.527
HPF1	VWA5B2	ENSACAP00000015377	ENSACAP00000008764	Histone PARylation factor 1.	Von Willebrand factor A domain containing 5B2.	0.522
KIF9	TICRR	ENSACAP00000005338	ENSACAP00000008090	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	TOPBP1 interacting checkpoint and replication regulator.	0.411
KIF9	VWA5B2	ENSACAP00000005338	ENSACAP00000008764	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Von Willebrand factor A domain containing 5B2.	0.546
KIF9	clba1	ENSACAP00000005338	ENSACAP00000018011	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Clathrin_bdg domain-containing protein.	0.545
LRATD2	TICRR	ENSACAP00000010161	ENSACAP00000008090	LRAT domain containing 2.	TOPBP1 interacting checkpoint and replication regulator.	0.405
LRATD2	VWA5B2	ENSACAP00000010161	ENSACAP00000008764	LRAT domain containing 2.	Von Willebrand factor A domain containing 5B2.	0.529
LRATD2	clba1	ENSACAP00000010161	ENSACAP00000018011	LRAT domain containing 2.	Clathrin_bdg domain-containing protein.	0.531
PARG	FEN1	ENSACAP00000020647	ENSACAP00000019151	Poly(ADP-ribose) glycohydrolase.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.697
PARG	HPF1	ENSACAP00000020647	ENSACAP00000015377	Poly(ADP-ribose) glycohydrolase.	Histone PARylation factor 1.	0.527