STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnmt3bPHD-type domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (358 aa)    
Predicted Functional Partners:
dnmt3l
PHD-type domain-containing protein.
  
 
0.958
DNMT1
DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 0.895
EZH1
Enhancer of zeste 1 polycomb repressive complex 2 subunit.
   
 0.655
EZH2
Enhancer of zeste 2 polycomb repressive complex 2 subunit.
   
 0.655
EED
Embryonic ectoderm development.
    
 0.607
ASH1L
ASH1 like histone lysine methyltransferase.
    
 0.596
setd1a
Uncharacterized protein.
    
 0.596
PRDM2
PR/SET domain 2.
      
 0.593
rbbp4
RB binding protein 4, chromatin remodeling factor.
   
 0.570
SETD2
SET domain containing 2, histone lysine methyltransferase.
    
 0.540
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.