STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THTyrosine hydroxylase. (486 aa)    
Predicted Functional Partners:
DBH
Dopamine beta-hydroxylase.
   
  
 0.817
PCBD2
Pterin-4 alpha-carbinolamine dehydratase 2.
  
 0.754
PNMT
Phenylethanolamine N-methyltransferase.
      
 0.754
PCBD1
Pterin-4 alpha-carbinolamine dehydratase 1.
  
 0.754
NPY
Neuropeptide Y.
   
  
 0.687
HGD
Homogentisate 1,2-dioxygenase.
  
  
 0.665
PVALB
Parvalbumin; Belongs to the parvalbumin family.
      
 0.659
BDNF
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
      
 0.630
CALB1
Calbindin 1.
      
 0.625
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
  
 0.620
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.