node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FLT4 | HGF | ENSACAP00000015679 | ENSACAP00000013097 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | 0.749 |
FLT4 | IGF1 | ENSACAP00000015679 | ENSACAP00000016240 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Insulin like growth factor 1. | 0.650 |
FLT4 | PDGFA | ENSACAP00000015679 | ENSACAP00000000392 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. | 0.714 |
FLT4 | PDGFB | ENSACAP00000015679 | ENSACAP00000023083 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. | 0.883 |
FLT4 | PDGFC | ENSACAP00000015679 | ENSACAP00000016585 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Platelet derived growth factor C. | 0.885 |
FLT4 | PDGFD | ENSACAP00000015679 | ENSACAP00000011655 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Platelet derived growth factor D. | 0.697 |
FLT4 | PGF | ENSACAP00000015679 | ENSACAP00000016515 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. | 0.944 |
FLT4 | VEGFA | ENSACAP00000015679 | ENSACAP00000001610 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. | 0.919 |
FLT4 | VEGFC | ENSACAP00000015679 | ENSACAP00000005834 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. | 0.994 |
FLT4 | VEGFD | ENSACAP00000015679 | ENSACAP00000012204 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. | 0.951 |
HGF | FLT4 | ENSACAP00000013097 | ENSACAP00000015679 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.749 |
HGF | IGF1 | ENSACAP00000013097 | ENSACAP00000016240 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Insulin like growth factor 1. | 0.903 |
HGF | PDGFA | ENSACAP00000013097 | ENSACAP00000000392 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. | 0.900 |
HGF | PDGFB | ENSACAP00000013097 | ENSACAP00000023083 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. | 0.914 |
HGF | PDGFC | ENSACAP00000013097 | ENSACAP00000016585 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Platelet derived growth factor C. | 0.917 |
HGF | PDGFD | ENSACAP00000013097 | ENSACAP00000011655 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Platelet derived growth factor D. | 0.914 |
HGF | PGF | ENSACAP00000013097 | ENSACAP00000016515 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. | 0.941 |
HGF | VEGFA | ENSACAP00000013097 | ENSACAP00000001610 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. | 0.937 |
HGF | VEGFC | ENSACAP00000013097 | ENSACAP00000005834 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. | 0.933 |
HGF | VEGFD | ENSACAP00000013097 | ENSACAP00000012204 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. | 0.918 |