STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRAK1Interleukin 1 receptor associated kinase 1. (679 aa)    
Predicted Functional Partners:
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.998
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.989
TOLLIP
Toll interacting protein.
   
 0.977
irak4
Interleukin 1 receptor associated kinase 4.
  
0.974
PELI1
Pellino E3 ubiquitin protein ligase 1.
    
 0.947
PELI2
Pellino E3 ubiquitin protein ligase family member 2.
    
 0.916
IRAK2
Interleukin 1 receptor associated kinase 2.
  
 
0.876
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.854
TLR4
Toll like receptor 4; Belongs to the Toll-like receptor family.
   
 0.852
IL1R1
Interleukin 1 receptor type 1.
    
 0.845
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.