STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEP57Centrosomal protein 57. (494 aa)    
Predicted Functional Partners:
PLK1
Polo like kinase 1.
     
 0.648
TRIP13
Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family.
   
  
 0.633
CEP63
Centrosomal protein 63.
    
 
 0.603
PLK4
Polo like kinase 4.
     
 0.588
BORA
BORA aurora kinase A activator.
   
 
  0.581
TMLHE
Trimethyllysine hydroxylase, epsilon.
      
 0.519
G1KIN8_ANOCA
Uncharacterized protein.
   
 
  0.511
DEUP1
Deuterosome assembly protein 1.
    
 
 0.479
PLK2
Serine/threonine-protein kinase PLK.
     
 0.478
PLK3
Serine/threonine-protein kinase PLK.
     
 0.478
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.