STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFSF12TNF superfamily member 12; Belongs to the tumor necrosis factor family. (191 aa)    
Predicted Functional Partners:
TNFSF13B
TNF superfamily member 13b; Belongs to the tumor necrosis factor family.
   
 0.910
tnfrsf12a
Uncharacterized protein.
    
 0.879
TNFSF11
TNF superfamily member 11; Belongs to the tumor necrosis factor family.
     
 0.853
POLR2A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
    
 0.684
R4GDK3_ANOCA
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
 
 
 0.661
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.585
LIG4
DNA ligase.
      
 0.583
MAP3K14
Mitogen-activated protein kinase kinase kinase 14.
     
 0.580
TRAF5
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.569
TNFRSF11A
TNF receptor superfamily member 11a.
     
 0.561
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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