STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF7Interferon regulatory factor 7. (475 aa)    
Predicted Functional Partners:
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.943
IRF3
Interferon regulatory factor 3.
     
0.858
TBK1
TANK binding kinase 1.
   
 0.821
TLR3
Toll like receptor 3; Belongs to the Toll-like receptor family.
   
 
 0.809
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.802
isg15
Uncharacterized protein.
   
 0.791
CREBBP
CREB binding protein.
    
 0.776
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.771
TANK
TRAF family member associated NFKB activator.
    
 0.745
IKBKE
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
   
 0.738
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (16%) [HD]