STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDKN3Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (211 aa)    
Predicted Functional Partners:
DLGAP5
DLG associated protein 5.
   
  
 0.946
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 
 0.860
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 
 0.831
CDK3
Cyclin dependent kinase 3; Belongs to the protein kinase superfamily.
   
 
 0.831
NDC80
NDC80 kinetochore complex component.
   
 
 0.779
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
  
 0.774
CDC20
Cell division cycle 20.
   
 0.764
CDC20B
Cell division cycle 20B.
   
 0.764
NUF2
NUF2 component of NDC80 kinetochore complex.
   
 
 0.763
KIF11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.741
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.