STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pou3f3POU domain protein. (454 aa)    
Predicted Functional Partners:
SOX1
SRY-box transcription factor 1.
  
 0.797
WT1
WT1 transcription factor.
    
 0.706
LMX1B
LIM homeobox transcription factor 1 beta.
    
 0.691
RFX4
Regulatory factor X4.
   
 
 0.691
TBX20
T-box transcription factor 20.
   
  
 0.689
ETS1
ETS proto-oncogene 1, transcription factor.
   
  
 0.689
PTCH1
Patched 1.
      
 0.688
IRX1
Iroquois homeobox 1.
   
  
 0.455
PCF11
PCF11 cleavage and polyadenylation factor subunit.
     
 0.440
LOC103282884
Uncharacterized protein.
    
  0.434
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (26%) [HD]