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mutL protein (Idiomarina loihiensis) - STRING interaction network
"mutL" - DNA mismatch repair enzyme, ATPase in Idiomarina loihiensis
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second shell of interactors
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some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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mutLDNA mismatch repair enzyme, ATPase; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (577 aa)    
Predicted Functional Partners:
mutS
Mismatch repair ATPase; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity (843 aa)
 
  0.999
mutH
DNA mismatch repair protein; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (224 aa)
       
  0.981
recA
Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (372 aa)
   
  0.972
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (316 aa)
 
     
  0.971
polA
DNA polymerase I (921 aa)
   
  0.949
IL0328
Fused sugar kinase/hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (506 aa)
 
   
  0.945
IL0329
Hypothetical protein (152 aa)
 
   
  0.928
uvrD
DNA-dependent helicase II (723 aa)
   
 
  0.924
rep
Rep helicase, a single-stranded DNA dependent ATPase; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3’ to 5’ direction (669 aa)
   
 
  0.924
hfq
Host factor I-like protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (85 aa)
 
     
  0.920
Your Current Organism:
Idiomarina loihiensis
NCBI taxonomy Id: 283942
Other names: I. loihiensis, I. loihiensis L2TR, Idiomarina loihiensis, Idiomarina loihiensis Donachie et al. 2003, Idiomarina loihiensis L2TR, Idiomarina loihiensis str. L2TR, Idiomarina loihiensis strain L2TR
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