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lepA protein (Idiomarina loihiensis) - STRING interaction network
"lepA" - Membrane GTPase LepA in Idiomarina loihiensis
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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lepAMembrane GTPase LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (603 aa)    
Predicted Functional Partners:
lepB
Signal peptidase I (306 aa)
   
   
  0.962
rnc
RNase III, dsRNA-specific ribonuclease; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism (229 aa)
 
 
  0.940
era
GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (305 aa)
 
   
  0.932
recO
Recombinational DNA repair protein RecO, RecF pathway; Involved in DNA repair and RecF pathway recombination (234 aa)
   
   
  0.905
prfA
Protein chain release factor A; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (364 aa)
 
   
  0.890
gltB
Glutamate synthase subunit alpha (1488 aa)
   
   
  0.869
gidA
NAD/FAD-utilizing enzyme apparently involved in cell division; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (631 aa)
 
   
  0.845
pheS
Phenylalanyl-tRNA synthetase alpha subunit (326 aa)
 
   
  0.835
leuS
Leucyl-tRNA synthetase (858 aa)
 
   
  0.826
pdxJ
Pyridoxine 5’-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5’-phosphate (PNP) and inorganic phosphate (242 aa)
   
   
  0.814
Your Current Organism:
Idiomarina loihiensis
NCBI taxonomy Id: 283942
Other names: I. loihiensis, I. loihiensis L2TR, Idiomarina loihiensis, Idiomarina loihiensis Donachie et al. 2003, Idiomarina loihiensis L2TR, Idiomarina loihiensis str. L2TR, Idiomarina loihiensis strain L2TR
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