STRINGSTRING
rseA protein (Idiomarina loihiensis) - STRING interaction network
"rseA" - Negative regulator of sigma E activity in Idiomarina loihiensis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rseANegative regulator of sigma E activity; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic prote [...] (195 aa)    
Predicted Functional Partners:
rpoE
RNA polymerase sigma factor RpoE (192 aa)
   
 
  0.996
rseB
Negative regulator of sigma E activity (321 aa)
   
 
  0.989
rseC
Positive regulator of sigma E activity (147 aa)
 
   
  0.942
IL1391
RNA polymerase sigma factor (206 aa)
 
 
  0.910
IL2423
DNA-directed RNA polymerase specialized sigma factor (357 aa)
   
 
  0.894
IL1936
DNA-directed RNA polymerase specialized sigma subunit (175 aa)
   
 
  0.894
fecI
DNA-directed RNA polymerase specialized sigma subunit (196 aa)
   
 
  0.894
IL0054
DNA-directed RNA polymerase specialized sigma subunit (180 aa)
   
 
  0.894
IL0838
Membrane-associated Zn-dependent protease (451 aa)
     
 
  0.794
ftsL
Cell division protein, FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (105 aa)
   
 
      0.776
Your Current Organism:
Idiomarina loihiensis
NCBI taxonomy Id: 283942
Other names: I. loihiensis, I. loihiensis L2TR, Idiomarina loihiensis, Idiomarina loihiensis Donachie et al. 2003, Idiomarina loihiensis L2TR, Idiomarina loihiensis str. L2TR, Idiomarina loihiensis strain L2TR
Server load: low (2%) [HD]