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seqA protein (Idiomarina loihiensis) - STRING interaction network
"seqA" - Replication initiation regulator SeqA in Idiomarina loihiensis
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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seqAReplication initiation regulator SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (160 aa)    
Predicted Functional Partners:
pgm
Phosphoglucomutase (545 aa)
   
        0.888
metJ
Transcriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (107 aa)
   
     
  0.883
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule (747 aa)
       
 
  0.823
IL1473
Alpha/beta hydrolase (258 aa)
 
        0.798
rraB
Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (128 aa)
   
          0.761
IL1265
Hypothetical protein (251 aa)
   
          0.755
mutH
DNA mismatch repair protein; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (224 aa)
   
     
  0.752
fadR
Fatty acid metabolism regulator; Multifunctional regulator of fatty acid metabolism (236 aa)
   
     
  0.747
IL1401
Zn-ribbon protein (69 aa)
   
          0.738
IL0678
Alkaline phosphatase (544 aa)
   
          0.737
Your Current Organism:
Idiomarina loihiensis
NCBI taxonomy Id: 283942
Other names: I. loihiensis, I. loihiensis L2TR, Idiomarina loihiensis, Idiomarina loihiensis Donachie et al. 2003, Idiomarina loihiensis L2TR, Idiomarina loihiensis str. L2TR, Idiomarina loihiensis strain L2TR
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