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birA protein (Idiomarina loihiensis) - STRING interaction network
"birA" - Biotin--protein ligase in Idiomarina loihiensis
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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birABiotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5’-adenylate (BirA-bio- 5’-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon (331 aa)    
Predicted Functional Partners:
oadA
Oxaloacetate decarboxylase (603 aa)
 
  0.994
accB
acetyl-CoA carboxylase biotin carboxyl carrier protein (151 aa)
 
  0.976
coaX
Transcriptional regulator; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (262 aa)
 
   
  0.969
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (345 aa)
   
 
  0.959
accC
acetyl-CoA carboxylase biotin carboxylase subunit (449 aa)
  0.952
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation (333 aa)
   
   
  0.939
IL0875
3-methylcrotonyl CoA carboxylase subunit beta (535 aa)
   
  0.898
IL2005
Na+/proline symporter (1157 aa)
   
   
  0.871
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1295 aa)
 
     
  0.867
IL0877
3-methylcrotonyl-CoA carboxylase subunit alpha (656 aa)
 
  0.867
Your Current Organism:
Idiomarina loihiensis
NCBI taxonomy Id: 283942
Other names: I. loihiensis, I. loihiensis L2TR, Idiomarina loihiensis, Idiomarina loihiensis Donachie et al. 2003, Idiomarina loihiensis L2TR, Idiomarina loihiensis str. L2TR, Idiomarina loihiensis strain L2TR
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