Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
Automated, unsupervised textmining - searching for proteins that are frequently mentioned together.
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Signal transduction histidine kinase (472 aa)
Predicted Functional Partners:
Metal-dependent hydrolase (258 aa)
DNA-directed RNA polymerase sigma 70 subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth (609 aa)
Hypothetical protein (407 aa)
ABC transporter substrate-binding protein (428 aa)
Copper export protein (281 aa)
Hypothetical protein (215 aa)
Hypothetical protein (559 aa)
Hypothetical protein (264 aa)
Capsular polyglutamate biosynthesis membrane protein CapC (191 aa)
Hypothetical protein (581 aa)
Your Current Organism:
NCBI taxonomy Id: 283942 Other names: I. loihiensis, I. loihiensis L2TR, Idiomarina loihiensis, Idiomarina loihiensis Donachie et al. 2003, Idiomarina loihiensis L2TR, Idiomarina loihiensis str. L2TR, Idiomarina loihiensis strain L2TR