node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
apt | gmk | IL1850 | IL2382 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.964 |
apt | gpt | IL1850 | IL0887 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.921 |
apt | guaA | IL1850 | IL0579 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.996 |
apt | ushA | IL1850 | IL1668 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.920 |
gmk | apt | IL2382 | IL1850 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.964 |
gmk | gpt | IL2382 | IL0887 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.911 |
gmk | guaA | IL2382 | IL0579 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.968 |
gmk | ndk | IL2382 | IL2038 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.934 |
gmk | nrdA | IL2382 | IL1363 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleotide reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.912 |
gmk | nrdB | IL2382 | IL1364 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleotide reductase, beta subunit. | 0.907 |
gmk | pykA | IL2382 | IL1263 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase II, glucose stimulated; Belongs to the pyruvate kinase family. | 0.917 |
gmk | rpoZ | IL2382 | IL2381 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.966 |
gmk | spoT | IL2382 | IL2380 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | (p)ppGpp synthetase I; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.950 |
gmk | ushA | IL2382 | IL1668 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.901 |
gpt | apt | IL0887 | IL1850 | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.921 |
gpt | gmk | IL0887 | IL2382 | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.911 |
gpt | guaA | IL0887 | IL0579 | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.910 |
gpt | ushA | IL0887 | IL1668 | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.900 |
guaA | apt | IL0579 | IL1850 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.996 |
guaA | gmk | IL0579 | IL2382 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.968 |