| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KOO37336.1 | KOO41159.1 | AMD01_22985 | AMD01_19665 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 3-hexulose-6-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.797 |
| KOO37336.1 | KOO44328.1 | AMD01_22985 | AMD01_13695 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Butanediol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.744 |
| KOO37336.1 | KOO46421.1 | AMD01_22985 | AMD01_11365 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.914 |
| KOO37336.1 | glyA | AMD01_22985 | AMD01_22725 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.419 |
| KOO37336.1 | pfkA | AMD01_22985 | AMD01_03700 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.463 |
| KOO37336.1 | pgi | AMD01_22985 | AMD01_04710 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. | 0.484 |
| KOO37336.1 | rpiA | AMD01_22985 | AMD01_01240 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.866 |
| KOO41158.1 | KOO41159.1 | AMD01_19660 | AMD01_19665 | 6-phospho 3-hexuloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-hexulose-6-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| KOO41158.1 | KOO46421.1 | AMD01_19660 | AMD01_11365 | 6-phospho 3-hexuloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.697 |
| KOO41158.1 | KOO50713.1 | AMD01_19660 | AMD01_02945 | 6-phospho 3-hexuloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Oxalate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.708 |
| KOO41158.1 | pfkA | AMD01_19660 | AMD01_03700 | 6-phospho 3-hexuloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.723 |
| KOO41158.1 | pgi | AMD01_19660 | AMD01_04710 | 6-phospho 3-hexuloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. | 0.844 |
| KOO41158.1 | rpiA | AMD01_19660 | AMD01_01240 | 6-phospho 3-hexuloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.731 |
| KOO41159.1 | KOO37336.1 | AMD01_19665 | AMD01_22985 | 3-hexulose-6-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 0.797 |
| KOO41159.1 | KOO41158.1 | AMD01_19665 | AMD01_19660 | 3-hexulose-6-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6-phospho 3-hexuloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| KOO41159.1 | KOO44328.1 | AMD01_19665 | AMD01_13695 | 3-hexulose-6-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Butanediol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.651 |
| KOO41159.1 | KOO46421.1 | AMD01_19665 | AMD01_11365 | 3-hexulose-6-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.708 |
| KOO41159.1 | KOO46837.1 | AMD01_19665 | AMD01_07920 | 3-hexulose-6-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Metal-dependent hydrolase; Catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0173 family. | 0.614 |
| KOO41159.1 | KOO50713.1 | AMD01_19665 | AMD01_02945 | 3-hexulose-6-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Oxalate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.672 |
| KOO41159.1 | glyA | AMD01_19665 | AMD01_22725 | 3-hexulose-6-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.674 |