STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PALI1_KLULApH-response regulator palI/RIM9 homolog 1; Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH; Belongs to the palI/RIM9 family. (220 aa)    
Predicted Functional Partners:
RIM21
pH-response regulator protein palH/RIM21; Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH; Belongs to the palH/RIM21 family.
    
 
 0.468
RIM101
pH-response transcription factor pacC/RIM101; Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including RIM101 itself) and represses transcription of acid- expressed genes (By similarity); Belongs to the pacC/RIM101 family.
   
 0.461
KLLA0_E16831g
KLLA0E16831p.
    
 
 0.439
RIM13
Calpain-like protease palB/RIM13; Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
    
 
 0.426
RIM8
pH-response regulator protein palF/RIM8; Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
   
 
 0.419
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
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