STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLLA0_D01705gKLLA0D01705p. (321 aa)    
Predicted Functional Partners:
KLLA0_F07161g
Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
    
 0.982
KLLA0_E17975g
KLLA0E17975p.
     
 0.980
KLLA0_D10846g
CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.
    
 0.973
KLLA0_A02167g
Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
   
 0.962
KLLA0_C13387g
KLLA0C13387p.
    
 0.649
KLLA0_C12001g
KLLA0C12001p.
    
 0.649
KLLA0_A07711g
KLLA0A07711p.
    
 
 0.541
KLLA0_D15631g
KLLA0D15631p.
      
 0.459
KLLA0_F27005g
KLLA0F27005p.
     
 0.457
COG6
Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events (By similarity); Belongs to the COG6 family.
    
   0.436
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.