KEX1-2 protein (Kluyveromyces lactis) - STRING interaction network

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KEX1-2

Pheromone-processing carboxypeptidase KEX1; Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity). (642 aa)

Predicted Functional Partners:

KEX1

0.605

KLLA0_E10649g

0.588

NMA111

0.565

KLLA0_D15136g

0.461

KLLA0_D06919g

0.461

BRE1

0.420

KLLA0_D05929g

0.419

KLLA0_D01507g

0.419

Your Current Organism:

Kluyveromyces lactis

NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRE1	KEX1	Q6CWM4	P09231	E3 ubiquitin-protein ligase BRE1; E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation; Belongs to the BRE1 family.	Protease KEX1; Probably involved in the processing of the precursor of m1- toxin and alpha-factor.	0.589
BRE1	KEX1-2	Q6CWM4	Q6CKK4	E3 ubiquitin-protein ligase BRE1; E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation; Belongs to the BRE1 family.	Pheromone-processing carboxypeptidase KEX1; Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).	0.420
KEX1	BRE1	P09231	Q6CWM4	Protease KEX1; Probably involved in the processing of the precursor of m1- toxin and alpha-factor.	E3 ubiquitin-protein ligase BRE1; E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation; Belongs to the BRE1 family.	0.589
KEX1	KEX1-2	P09231	Q6CKK4	Protease KEX1; Probably involved in the processing of the precursor of m1- toxin and alpha-factor.	Pheromone-processing carboxypeptidase KEX1; Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).	0.605
KEX1	KLLA0_D01507g	P09231	Q6CSF3	Protease KEX1; Probably involved in the processing of the precursor of m1- toxin and alpha-factor.	KLLA0D01507p; Belongs to the peptidase A1 family.	0.431
KEX1	KLLA0_D05929g	P09231	Q6CRW3	Protease KEX1; Probably involved in the processing of the precursor of m1- toxin and alpha-factor.	KLLA0D05929p; Belongs to the peptidase A1 family.	0.447
KEX1	KLLA0_D06919g	P09231	Q6CRS0	Protease KEX1; Probably involved in the processing of the precursor of m1- toxin and alpha-factor.	KLLA0D06919p; Belongs to the peptidase S9B family.	0.633
KEX1-2	BRE1	Q6CKK4	Q6CWM4	Pheromone-processing carboxypeptidase KEX1; Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).	E3 ubiquitin-protein ligase BRE1; E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation; Belongs to the BRE1 family.	0.420
KEX1-2	KEX1	Q6CKK4	P09231	Pheromone-processing carboxypeptidase KEX1; Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).	Protease KEX1; Probably involved in the processing of the precursor of m1- toxin and alpha-factor.	0.605
KEX1-2	KLLA0_D01507g	Q6CKK4	Q6CSF3	Pheromone-processing carboxypeptidase KEX1; Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).	KLLA0D01507p; Belongs to the peptidase A1 family.	0.419
KEX1-2	KLLA0_D05929g	Q6CKK4	Q6CRW3	Pheromone-processing carboxypeptidase KEX1; Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).	KLLA0D05929p; Belongs to the peptidase A1 family.	0.419
KEX1-2	KLLA0_D06919g	Q6CKK4	Q6CRS0	Pheromone-processing carboxypeptidase KEX1; Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).	KLLA0D06919p; Belongs to the peptidase S9B family.	0.461
KEX1-2	KLLA0_D15136g	Q6CKK4	Q6CQQ7	Pheromone-processing carboxypeptidase KEX1; Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).	KLLA0D15136p.	0.461
KEX1-2	KLLA0_E10649g	Q6CKK4	Q6CNQ8	Pheromone-processing carboxypeptidase KEX1; Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).	Tryptophan synthase.	0.588
KEX1-2	NMA111	Q6CKK4	Q6CIT6	Pheromone-processing carboxypeptidase KEX1; Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).	Pro-apoptotic serine protease NMA111; Nuclear serine protease which mediates apoptosis. Belongs to the peptidase S1C family.	0.565
KLLA0_D01507g	KEX1	Q6CSF3	P09231	KLLA0D01507p; Belongs to the peptidase A1 family.	Protease KEX1; Probably involved in the processing of the precursor of m1- toxin and alpha-factor.	0.431
KLLA0_D01507g	KEX1-2	Q6CSF3	Q6CKK4	KLLA0D01507p; Belongs to the peptidase A1 family.	Pheromone-processing carboxypeptidase KEX1; Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).	0.419
KLLA0_D05929g	KEX1	Q6CRW3	P09231	KLLA0D05929p; Belongs to the peptidase A1 family.	Protease KEX1; Probably involved in the processing of the precursor of m1- toxin and alpha-factor.	0.447
KLLA0_D05929g	KEX1-2	Q6CRW3	Q6CKK4	KLLA0D05929p; Belongs to the peptidase A1 family.	Pheromone-processing carboxypeptidase KEX1; Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).	0.419
KLLA0_D06919g	KEX1	Q6CRS0	P09231	KLLA0D06919p; Belongs to the peptidase S9B family.	Protease KEX1; Probably involved in the processing of the precursor of m1- toxin and alpha-factor.	0.633

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