STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOG1Mitogen-activated protein kinase HOG1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily. (444 aa)    
Predicted Functional Partners:
KLLA0_D08030g
KLLA0D08030p.
    
 0.993
KLLA0_A10219g
KLLA0A10219p.
    
 0.988
KLLA0_E15313g
KLLA0E15313p.
  
0.985
KLLA0_C07733g
KLLA0C07733p.
    
 0.980
KLLA0_F14729g
KLLA0F14729p.
   
 0.979
KLLA0_D06611g
KLLA0D06611p.
    
 0.976
HOT1
High-osmolarity-induced transcription protein 1; Required for a complete transcriptional response to osmotic stress; Belongs to the HOT1 family.
   
 0.970
KLLA0_F26961g
KLLA0F26961p.
    
 0.948
SHO1
High osmolarity signaling protein SHO1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
    
 
 0.930
KLLA0_F13552g
KLLA0F13552p.
  
 
 
0.923
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
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